MicroMatrices specialises in high resolution cell type-specific analysis to characterise toxicological responses in different cell types in the tissue. This facilitates the design of in vitro models for screening and assessment of the relevance of mechanisms identified in vivo to man.
Services can be provided in the context of in vivo and in vitro toxicological models and integrated with conventional toxicity end-points, including in situ hybridisation (ISH) and histopathological data. We provide image analysis for quantitative immunostaining and ISH analysis.
MicroMatrices are capable of retrospective study analysis, whereby we successfully extract RNA from archival FFPE tissue blocks to be used in our integrated miRNA and mRNA array studies.
This obviates the need for new animal experiments, unlocking the potential of historic samples for new investigative studies such as identifying potential biomarkers for future screening and mechanistic studies.
Please contact us to discuss your project.
on an interactive, step by step basis. Collaborations can begin with pilot projects which can then be scaled up to larger research programs, according to your requirements.