Frontiers, Not Boundaries

Cross Species Risk Assessment in 3D Microtissues-SOT2020

4th March 2020

We look forward to meeting clients and colleagues at the 59th annual meeting of the Society of Toxicology, held this year between 15-19 March in Anaheim, California.

We will be presenting a poster entitled “Species differences in phenobarbital-mediated UGT gene induction in rat and human liver 3D microtissues”  (P340) in which we will describe how we have  used rodent and liver microtissues to investigate the hypothesis that inter-species differences in induction within the UGT promoter regions account for the well described differences between rodent and human susceptibility to liver tumor induction by CAR activators.

Please get in touch if you will also be in Anaheim and would like to discuss  how our SpheroMatrices® microTMA technology for 3D microtissues can be  used for early discovery de-risking of test compounds.

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on an interactive, step by step basis. Collaborations can begin with pilot projects which can then be scaled up to larger research programs, according to your requirements.